• Expression and function of the miR-143/145 cluster in vitro and in vivo in human breast cancer 

      Johannessen, Charles; Moi, Line; Kiselev, Yury; Pedersen, Mona Irene; Dalen, Stig Manfred; Braaten, Tonje; Busund, Lill-Tove (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-26)
      MicroRNAs (miRNAs) are small non-coding RNAs that function as post-transcriptional regulators of gene expression and are dysregulated in cancer. Studies of miRNAs to explore their potential as diagnostic and prognostic markers are of great scientific interest. Here, we investigate the functional properties and expression of the miR-143/145 cluster in breast cancer (BC) in vitro and in vivo. The ER ...
    • Real-life evaluation of histologic scores for Ulcerative Colitis in remission 

      Arkteg, Christian Børde; Sørbye, Sveinung Wergeland; Riis, Lene Buhl; Dalen, Stig Manfred; Florholmen, Jon; Goll, Rasmus (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-08)
      Background - Histological evaluation of ulcerative colitis (UC) patients has been debated ever since the first description of the disease and its role in follow-up has never been fully established. Recent evidence suggests an added benefit in accuracy when evaluating if the patient is in remission. Unfortunately, there are several different histological indices, and it is difficult to compare outcomes ...